Neuroscience Research Collaboration between ETHZ, University of Tokyo and RIKEN
An international collaboration between the Bio Engineering Laboratory at ETHZ, the Kanzaki-Takahashi Lab at the University of Tokyo, and Prof. Urs Frey from the Frey Initiative Research Unit at the RIKEN Quantitative Biology Centre in Kobe recently published the results of an avant-garde research in the highly renown journal Nature Communications (“Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites“).
Axons are usually a long process of a nerve fiber that generally conducts electrical impulses from one neuron to another. To carry out the challenging extracellular electrical recordings from nerve axons, they used high-resolution microelectrode arrays to electrically visualize action potential propagation on axons in cultured neuronal networks. The authors showed that axons can not be merely considered stable transmission cables, as they found large variations in propagation velocities within single axons, suggesting that the temporal control of their output may contribute to neuronal information processing.
Professor Urs Frey leads the Frey-IRU at RIKEN QBiC, a biosensors and bioelectronics laboratory that develops CMOS-based sensor devices targeting biological applications, especially in systems biology and systems neuroscience.